Be strategic with federal grants. Don’t apply for every one that comes along that might be remotely connected to your mission. Square peg, round hole. Either a grant is a good fit for your current program(s) and initiative(s) or it’s not. Don’t force it and don’t radically change your services and your focus just to accommodate a grant. If you’re going to invest the time applying for federal grants, you want to pursue the ones where you have a reasonable chance of being successful or, at the very least, highly competitive.